STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbbp8RB binding protein 8, endonuclease. (647 aa)    
Predicted Functional Partners:
brca1
BRCA1 DNA repair associated.
   
 0.999
bard1
BRCA1 associated RING domain 1.
    
 0.997
mre11
MRE11 homolog, double strand break repair nuclease.
   
 0.994
rad50
RAD50 double strand break repair protein.
    
 0.992
ankrd12
Ankyrin repeat domain 12.
    
 0.970
ankrd11
Ankyrin repeat domain 11.
    
 0.970
exo1
Exonuclease 1.
   
 0.949
atm
ATM serine/threonine kinase.
    
 0.935
palb2
Partner and localizer of BRCA2.
  
 0.875
dna2
DNA replication helicase/nuclease 2.
    
 0.870
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.