Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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yacGDNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (63 aa)    
Predicted Functional Partners:
AOR76147.1
Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.853
AOR78496.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.839
infA_1
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.766
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
    
 
 0.487
AOR78004.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.481
AOR78008.1
Phage major tail protein, TP901-1 family; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.480
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.472
AOR78001.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.468
AOR76145.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.465
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.453
Your Current Organism:
Novosphingobium resinovorum
NCBI taxonomy Id: 158500
Other names: ATCC 33545, CCUG 33446 A, CCUG 33446 B, CIP 105288 [[Novosphingobium subarcticum]], DSM 10700 [[Novosphingobium subarcticum]], DSM 7478, Flavobacterium resinovorum, HAMBI 2110 [[Novosphingobium subarcticum]], JCM 10398 [[Novosphingobium subarcticum]], LMG 8367, LMG:8367, N. resinovorum, NBRC 16058 [[Novosphingobium subarcticum]], NCIMB 8767, Novosphingobium subarcticum, Pseudomonas KF1, Pseudomonas KF3, Pseudomonas NKF1, Sphingomonas subarctica, strain KF1 [[Novosphingobium subarcticum]]
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