Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrBPeptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MsrB Met sulfoxide reductase family. (131 aa)    
Predicted Functional Partners:
msrA_1
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.994
AOR77249.1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.816
AOR78729.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
 
      0.673
AOR77068.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.593
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
 
 0.561
AOR77070.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
AOR78241.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.529
AOR76671.1
Succinate dehydrogenase, hydrophobic membrane anchor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.520
AOR76672.1
Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.516
AOR78723.1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.513
Your Current Organism:
Novosphingobium resinovorum
NCBI taxonomy Id: 158500
Other names: ATCC 33545, CCUG 33446 A, CCUG 33446 B, CIP 105288 [[Novosphingobium subarcticum]], DSM 10700 [[Novosphingobium subarcticum]], DSM 7478, Flavobacterium resinovorum, HAMBI 2110 [[Novosphingobium subarcticum]], JCM 10398 [[Novosphingobium subarcticum]], LMG 8367, LMG:8367, N. resinovorum, NBRC 16058 [[Novosphingobium subarcticum]], NCIMB 8767, Novosphingobium subarcticum, Pseudomonas KF1, Pseudomonas KF3, Pseudomonas NKF1, Sphingomonas subarctica, strain KF1 [[Novosphingobium subarcticum]]
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