STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHEL01_v207062ATP-dependent DNA helicase mph-1. (1105 aa)    
Predicted Functional Partners:
DHEL01_v208954
RMI1_N domain-containing protein.
    
 0.976
DHEL01_v207008
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.974
DHEL01_v201517
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.970
DHEL01_v201536
DNA repair protein rad10.
    
 0.965
DHEL01_v204430
Crossover junction endonuclease MUS81.
    
 0.957
DHEL01_v210345
zf-GRF domain-containing protein.
   
 0.949
DHEL01_v206164
NPL4 family protein.
    
 0.947
DHEL01_v210788
HRDC domain-containing protein.
   
 0.938
DHEL01_v202187
3'-5' exonuclease.
   
 0.938
DHEL01_v201958
Mutagen-sensitive-50.
    
 
 0.933
Your Current Organism:
Diaporthe helianthi
NCBI taxonomy Id: 158607
Other names: CBS 592.81, D. helianthi, Phomopsis helianthi, Phomopsis sp. CBS 187.87
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