STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHEL01_v200222SET domain-containing protein. (420 aa)    
Predicted Functional Partners:
DHEL01_v202565
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.870
DHEL01_v200017
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
    
 0.866
DHEL01_v201442
Set-domain histone methyltransferase-2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
     
 0.820
DHEL01_v208341
Histone-lysine N-methyltransferase SET9.
     
 0.801
DHEL01_v204358
Histone-lysine N-methyltransferase ASH1L.
     
 0.801
DHEL01_v211305
Chromo domain-containing protein.
    
 0.728
DHEL01_v204834
WD_REPEATS_REGION domain-containing protein.
    
 0.686
DHEL01_v201162
WD domain-containing protein.
    
 0.670
DHEL01_v212188
WD_REPEATS_REGION domain-containing protein.
    
 0.656
DHEL01_v202338
Ash2-trithorax family protein.
    
 0.656
Your Current Organism:
Diaporthe helianthi
NCBI taxonomy Id: 158607
Other names: CBS 592.81, D. helianthi, Phomopsis helianthi, Phomopsis sp. CBS 187.87
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.