STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recD2Exodeoxyribonuclease V subunit alpha; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (783 aa)    
Predicted Functional Partners:
ALI52810.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.873
ALI52809.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.793
addA
ATP-dependent helicase; ATP-dependent DNA helicase.
  
 
 0.775
ALI51691.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.768
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.763
mnmA
Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
    0.735
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.731
ALI52812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
ALI52664.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.662
ALI52146.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.629
Your Current Organism:
Lactobacillus helveticus
NCBI taxonomy Id: 1587
Other names: ATCC 15009, Bacillus casei e, Bacillus e, CCUG 30139, CIP 103146, Caseobacterium e, DSM 20075, IFO 15019, L. helveticus, LMG 13555, LMG 22464 [[Lactobacillus suntoryeus]], LMG 6413, LMG:13555, LMG:22464 [[Lactobacillus suntoryeus]], LMG:6413, Lactobacillus helveticum, Lactobacillus sp. NCIM 2126, Lactobacillus sp. NCIM 2733, Lactobacillus suntoryeus, Lactobacillus suntoryeus Cachat and Priest 2005, Lactobacterium helveticum, NBRC 15019, NCIMB 14005 [[Lactobacillus suntoryeus]], NRRL B-4526, Plocamobacterium helveticum, Thermobacterium helveticum, strain SA [[Lactobacillus suntoryeus]]
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