Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALI53012.1Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)    
Predicted Functional Partners:
ALI52069.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.603
ALI53011.1
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.552
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.479
ALI52059.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
  
    0.478
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
   
 0.478
ALI52682.1
Hemolysin III; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.412
Your Current Organism:
Lactobacillus helveticus
NCBI taxonomy Id: 1587
Other names: ATCC 15009, Bacillus casei e, Bacillus e, CCUG 30139, CIP 103146, Caseobacterium e, DSM 20075, IFO 15019, L. helveticus, LMG 13555, LMG 22464 [[Lactobacillus suntoryeus]], LMG 6413, LMG:13555, LMG:22464 [[Lactobacillus suntoryeus]], LMG:6413, Lactobacillus helveticum, Lactobacillus sp. NCIM 2126, Lactobacillus sp. NCIM 2733, Lactobacillus suntoryeus, Lactobacillus suntoryeus Cachat and Priest 2005, Lactobacterium helveticum, NBRC 15019, NCIMB 14005 [[Lactobacillus suntoryeus]], NRRL B-4526, Plocamobacterium helveticum, Thermobacterium helveticum, strain SA [[Lactobacillus suntoryeus]]
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