node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bglF_2 | boxD_1 | LH23_12010 | LH23_16450 | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
bglF_2 | folM | LH23_12010 | LH23_15245 | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
bglF_2 | fryA_2 | LH23_12010 | LH23_19905 | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.998 |
bglF_2 | porB | LH23_12010 | LH23_16365 | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
bglF_2 | ptsG_1 | LH23_12010 | LH23_11545 | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS N-acetyl glucosamine transporter subunits IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
boxD_1 | bglF_2 | LH23_16450 | LH23_12010 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
boxD_1 | folM | LH23_16450 | LH23_15245 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
boxD_1 | fryA_2 | LH23_16450 | LH23_19905 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.425 |
boxD_1 | gltB | LH23_16450 | LH23_03030 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.869 |
boxD_1 | nuoC | LH23_16450 | LH23_21605 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.437 |
boxD_1 | porB | LH23_16450 | LH23_16365 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
boxD_1 | ptsG_1 | LH23_16450 | LH23_11545 | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS N-acetyl glucosamine transporter subunits IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
folA | folM | LH23_08765 | LH23_15245 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.760 |
folA | thyA | LH23_08765 | LH23_01345 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.992 |
folM | bglF_2 | LH23_15245 | LH23_12010 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
folM | boxD_1 | LH23_15245 | LH23_16450 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
folM | folA | LH23_15245 | LH23_08765 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.760 |
folM | fryA_2 | LH23_15245 | LH23_19905 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.779 |
folM | gltB | LH23_15245 | LH23_03030 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
folM | nuoC | LH23_15245 | LH23_21605 | Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.844 |