STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ompCMembrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. (365 aa)    
Predicted Functional Partners:
ompA
Membrane protein; OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 0.985
tolB
Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 
 
 0.930
degP
Serine endoprotease; Protease Do; required at high temperature; degrades damaged proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
  
 
 
 0.884
mlaA
ABC transporter permease; Involved in maintaining OM lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.872
btuB
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.857
ompX
Membrane protein; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.777
lpoB
Penicillin-binding protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
     0.767
holD
DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.761
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.758
lpp
Major outer membrane lipoprotein; interacts with peptidoglycan to maintain the integrity of the cell envelope; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.758
Your Current Organism:
Cedecea neteri
NCBI taxonomy Id: 158822
Other names: ATCC 33855, C. neteri, CCUG 18763, CDC 0621-75, CIP 103241, Cedecea sp. M006, Cedecea sp. ND02, Cedecea sp. ND14a, Cedecea sp. ND14b, DSM 13693, JCM 7582, LMG 7864, LMG:7864, NBRC 105707, NCTC 12120, strain 002
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