node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB90602.1 | carA | HMPREF3182_01022 | HMPREF3182_00004 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | 0.952 |
KXB90602.1 | carB | HMPREF3182_01022 | HMPREF3182_00003 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | KEGG: med:MELS_0849 0. carbamoyl-phosphate synthase large chain; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.960 |
KXB90602.1 | purF | HMPREF3182_01022 | HMPREF3182_01025 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.679 |
KXB90602.1 | pyrB | HMPREF3182_01022 | HMPREF3182_00006 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | KEGG: med:MELS_0846 9.0e-128 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.943 |
KXB90602.1 | pyrC | HMPREF3182_01022 | HMPREF3182_00005 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
KXB90602.1 | pyrD | HMPREF3182_01022 | HMPREF3182_01023 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
KXB90602.1 | pyrE | HMPREF3182_01022 | HMPREF3182_01529 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.994 |
KXB90602.1 | pyrF | HMPREF3182_01022 | HMPREF3182_01530 | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.949 |
argG | carA | HMPREF3182_00201 | HMPREF3182_00004 | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | 0.936 |
argG | carB | HMPREF3182_00201 | HMPREF3182_00003 | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | KEGG: med:MELS_0849 0. carbamoyl-phosphate synthase large chain; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.993 |
argG | dapF | HMPREF3182_00201 | HMPREF3182_01255 | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.602 |
argG | purF | HMPREF3182_00201 | HMPREF3182_01025 | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.568 |
argG | pyrB | HMPREF3182_00201 | HMPREF3182_00006 | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | KEGG: med:MELS_0846 9.0e-128 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.933 |
carA | KXB90602.1 | HMPREF3182_00004 | HMPREF3182_01022 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | Oxidoreductase NAD-binding domain protein; KEGG: sri:SELR_16840 5.3e-52 pyrK; putative dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.26. | 0.952 |
carA | argG | HMPREF3182_00004 | HMPREF3182_00201 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | KEGG: med:MELS_0097 1.6e-192 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.936 |
carA | carB | HMPREF3182_00004 | HMPREF3182_00003 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | KEGG: med:MELS_0849 0. carbamoyl-phosphate synthase large chain; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.999 |
carA | dapF | HMPREF3182_00004 | HMPREF3182_01255 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.515 |
carA | purF | HMPREF3182_00004 | HMPREF3182_01025 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.941 |
carA | pyrB | HMPREF3182_00004 | HMPREF3182_00006 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | KEGG: med:MELS_0846 9.0e-128 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | HMPREF3182_00004 | HMPREF3182_00005 | Carbamoyl-phosphate synthase, small subunit; KEGG: med:MELS_0848 1.3e-151 carbamoyl-phosphate synthase; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |