STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (457 aa)    
Predicted Functional Partners:
KXB93143.1
KEGG: med:MELS_0139 2.5e-68 hypoxanthine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.991
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.918
tadA
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.855
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.846
KXB93145.1
KEGG: med:MELS_0141 2.6e-75 Ppx/GppA phosphatase; K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Psort location: Cytoplasmic, score: 9.26.
       0.802
KXB92347.1
Thiamine biosynthesis protein ThiS.
  
   0.789
KXB93147.1
Putative general stress protein 13; KEGG: bao:BAMF_0063 2.4e-33 yabR; polyribonucleotide nucleotidyltransferase or phosphorylase K07571; Psort location: Cytoplasmic, score: 9.97.
  
    0.748
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
  
 0.738
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
   
 0.706
KXB93146.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.701
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
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