STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (329 aa)    
Predicted Functional Partners:
KXB92976.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 0.998
KXB92978.1
Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.998
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.976
KXB92982.1
KEGG: med:MELS_0085 3.5e-133 arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.956
KXB92984.1
KEGG: med:MELS_0083 1.9e-93 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.942
kdsA
3-deoxy-8-phosphooctulonate synthase; KEGG: med:MELS_0086 1.7e-117 2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family.
 
   
 0.941
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.907
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.894
KXB92977.1
KEGG: med:MELS_0090 1.0e-236 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.882
KXB92975.1
Hypothetical protein; KEGG: hmc:HYPMC_2860 9.9e-22 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.873
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
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