node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB90657.1 | KXB90666.1 | HMPREF3182_01081 | HMPREF3182_01090 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.753 |
KXB90657.1 | KXB92696.1 | HMPREF3182_01081 | HMPREF3182_00358 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.884 |
KXB90657.1 | cinA | HMPREF3182_01081 | HMPREF3182_01498 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.936 |
KXB90657.1 | nadD | HMPREF3182_01081 | HMPREF3182_00357 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.959 |
KXB90657.1 | nadK | HMPREF3182_01081 | HMPREF3182_00025 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.915 |
KXB90657.1 | rsfS | HMPREF3182_01081 | HMPREF3182_00360 | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.841 |
KXB90666.1 | KXB90657.1 | HMPREF3182_01090 | HMPREF3182_01081 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | 0.753 |
KXB90666.1 | KXB92696.1 | HMPREF3182_01090 | HMPREF3182_00358 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.558 |
KXB90666.1 | cinA | HMPREF3182_01090 | HMPREF3182_01498 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 8.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family. | 0.933 |
KXB90666.1 | nadD | HMPREF3182_01090 | HMPREF3182_00357 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.909 |
KXB90666.1 | nadK | HMPREF3182_01090 | HMPREF3182_00025 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.435 |
KXB92691.1 | KXB92696.1 | HMPREF3182_00353 | HMPREF3182_00358 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | 0.702 |
KXB92691.1 | KXB92697.1 | HMPREF3182_00353 | HMPREF3182_00359 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Cell envelope-like function transcriptional attenuator common domain protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.503 |
KXB92691.1 | KXB92699.1 | HMPREF3182_00353 | HMPREF3182_00361 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: mai:MICA_2002 4.3e-25 3-deoxy-7-phosphoheptulonate synthase K00243; Psort location: Cytoplasmic, score: 8.96; Belongs to the CvfB family. | 0.503 |
KXB92691.1 | nadD | HMPREF3182_00353 | HMPREF3182_00357 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.843 |
KXB92691.1 | obg | HMPREF3182_00353 | HMPREF3182_00352 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.820 |
KXB92691.1 | rsfS | HMPREF3182_00353 | HMPREF3182_00360 | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.739 |
KXB92696.1 | KXB90657.1 | HMPREF3182_00358 | HMPREF3182_01081 | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | NAD+ synthase; KEGG: med:MELS_2113 1.4e-216 NAD+ synthetase; K01950 NAD+ synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.97. | 0.884 |
KXB92696.1 | KXB90666.1 | HMPREF3182_00358 | HMPREF3182_01090 | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.558 |
KXB92696.1 | KXB92691.1 | HMPREF3182_00358 | HMPREF3182_00353 | Hydrolase, HD family; KEGG: bqy:MUS_2859 2.0e-29 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 8.96. | 0.702 |