STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tadACytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (157 aa)    
Predicted Functional Partners:
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.922
KXB91083.1
GTP cyclohydrolase II; KEGG: med:MELS_0145 2.1e-87 riboflavin biosynthesis protein ribBA; K14652 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Psort location: Cytoplasmic, score: 9.97.
    
 0.916
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
 
 0.855
KXB91704.1
Exodeoxyribonuclease III; KEGG: med:MELS_1913 2.7e-112 exodeoxyribonuclease III; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.708
KXB92344.1
Putative thiamine-phosphate diphosphorylase; KEGG: med:MELS_0328 5.7e-71 thiamine-phosphate pyrophosphorylase; K00788 thiamine-phosphate pyrophosphorylase.
 
      0.659
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.636
KXB90125.1
KEGG: med:MELS_1225 5.4e-224 phosphoribulokinase/uridine kinase family protein; K00876 uridine kinase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.635
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 0.594
mtaD
Putative 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
    
 0.590
KXB91931.1
Hypothetical protein; KEGG: bqy:MUS_3662 2.8e-21 yvgT; thioredoxin reductase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.523
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.