Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.

Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]

Lipid kinase, YegS/Rv2252/BmrU family; KEGG: efc:EFAU004_00587 1.7e-62 diacylglycerol kinase catalytic subunit K07029; Psort location: Cytoplasmic, score: 9.97.

KEGG: med:MELS_2044 0. pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase.

Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]

Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.

Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.

Putative thioredoxin; KEGG: dat:HRM2_11650 1.3e-18 trxA1; protein TrxA1; K03672 thioredoxin 2; Psort location: Cytoplasmic, score: 9.26; Belongs to the thioredoxin family.