STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB91427.1Putative endoribonuclease L-PSP; KEGG: ape:APE_1501.1 7.1e-25 ribonuclease UK114 K01175; Psort location: Cytoplasmic, score: 9.26. (128 aa)    
Predicted Functional Partners:
KXB91426.1
KEGG: med:MELS_1276 4.4e-167 threonine ammonia-lyase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.757
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      0.756
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.664
KXB91428.1
Hypothetical protein.
       0.596
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
    
  0.582
KXB91030.1
Putative translation elongation factor G; KEGG: efu:HMPREF0351_10054 5.9e-60 fusA; protein-synthesizing GTPase K02355; Psort location: Cytoplasmic, score: 9.97.
    
  0.582
KXB90553.1
KEGG: ddf:DEFDS_1534 3.8e-152 translation elongation factor G K02355; Psort location: Cytoplasmic, score: 9.97.
    
  0.582
KXB90226.1
Aminotransferase, class IV; KEGG: med:MELS_1673 1.3e-50 aminotransferase; K02619 4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 9.26.
    
 0.553
KXB90678.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.499
KXB90160.1
KEGG: ain:Acin_2240 2.4e-56 apt; adenine phosphoribosyltransferase K00759.
  
 
 0.484
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
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