STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (182 aa)    
Predicted Functional Partners:
KXB91565.1
Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
 0.872
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.867
KXB91905.1
KEGG: med:MELS_2202 0. anaerobic ribonucleoside-triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 9.97.
    
  0.843
KXB90654.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.705
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.611
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.610
KXB90653.1
KEGG: med:MELS_1968 2.3e-212 DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
       0.562
KXB90656.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.531
KXB90689.1
MazG family protein; KEGG: bmq:BMQ_0078 1.5e-61 Tetrapyrrole (Corrin/Porphyrin) methylase, MazG protein K02499; Psort location: Cytoplasmic, score: 8.96.
     
 0.530
KXB91566.1
Hydrolase, NUDIX family; KEGG: med:MELS_2024 3.6e-53 hydrolase; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 8.96.
   
  0.523
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
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