node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB90778.1 | KXB92715.1 | HMPREF3182_01203 | HMPREF3182_00377 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.484 |
KXB90778.1 | KXB93099.1 | HMPREF3182_01203 | HMPREF3182_00015 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.959 |
KXB90778.1 | KXB93180.1 | HMPREF3182_01203 | HMPREF3182_00098 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily. | 0.539 |
KXB90778.1 | asd | HMPREF3182_01203 | HMPREF3182_00020 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.986 |
KXB90778.1 | carB | HMPREF3182_01203 | HMPREF3182_00003 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | KEGG: med:MELS_0849 0. carbamoyl-phosphate synthase large chain; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.453 |
KXB90778.1 | dapA | HMPREF3182_01203 | HMPREF3182_00019 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.797 |
KXB90778.1 | dapB | HMPREF3182_01203 | HMPREF3182_00021 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.809 |
KXB90778.1 | dapF | HMPREF3182_01203 | HMPREF3182_01255 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.688 |
KXB90778.1 | murE | HMPREF3182_01203 | HMPREF3182_00254 | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.557 |
KXB91566.1 | dapF | HMPREF3182_00788 | HMPREF3182_01255 | Hydrolase, NUDIX family; KEGG: med:MELS_2024 3.6e-53 hydrolase; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.686 |
KXB92715.1 | KXB90778.1 | HMPREF3182_00377 | HMPREF3182_01203 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | 0.484 |
KXB92715.1 | KXB93099.1 | HMPREF3182_00377 | HMPREF3182_00015 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | 0.501 |
KXB92715.1 | carB | HMPREF3182_00377 | HMPREF3182_00003 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: med:MELS_0849 0. carbamoyl-phosphate synthase large chain; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.498 |
KXB92715.1 | dapB | HMPREF3182_00377 | HMPREF3182_00021 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.420 |
KXB92715.1 | dapF | HMPREF3182_00377 | HMPREF3182_01255 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.626 |
KXB92715.1 | murE | HMPREF3182_00377 | HMPREF3182_00254 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.414 |
KXB93099.1 | KXB90778.1 | HMPREF3182_00015 | HMPREF3182_01203 | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | Aspartate kinase, monofunctional class; KEGG: med:MELS_2095 1.8e-170 aspartokinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. | 0.959 |
KXB93099.1 | KXB92715.1 | HMPREF3182_00015 | HMPREF3182_00377 | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.501 |
KXB93099.1 | KXB93180.1 | HMPREF3182_00015 | HMPREF3182_00098 | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily. | 0.733 |
KXB93099.1 | asd | HMPREF3182_00015 | HMPREF3182_00020 | KEGG: med:MELS_1258 5.4e-185 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 9.97. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.639 |