STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB90160.1KEGG: ain:Acin_2240 2.4e-56 apt; adenine phosphoribosyltransferase K00759. (184 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 0.966
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.875
ade
KEGG: ldl:LBU_0901 2.7e-238 Adenine deaminase 1; K01486 adenine deaminase; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.853
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.808
KXB92603.1
Adenylosuccinate lyase; KEGG: med:MELS_0685 8.1e-198 adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
  
 0.802
KXB90159.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
 0.801
KXB90608.1
KEGG: med:MELS_1629 2.1e-71 MGS-like domain protein; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97.
  
 0.746
deoD
KEGG: med:MELS_1150 1.2e-93 purine nucleoside phosphorylase deoD-type; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.97.
     
 0.737
KXB90546.1
KEGG: med:MELS_0569 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: CytoplasmicMembrane, score: 8.46.
  
  
 0.726
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.720
Your Current Organism:
Veillonellaceae bacterium KA00182
NCBI taxonomy Id: 1588748
Other names: V. bacterium KA00182
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