STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB54191.1UvrD/REP helicase; KEGG: cpi:Cpin_0896 7.8e-62 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97; Belongs to the helicase family. UvrD subfamily. (1165 aa)    
Predicted Functional Partners:
KXB48974.1
KEGG: eyy:EGYY_25950 0. RecJ; single-stranded DNA-specific exonuclease; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.89.
  
 0.992
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.906
KXB52660.1
DnaQ family exonuclease/DinG family helicase; KEGG: eyy:EGYY_29890 7.5e-195 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97.
  
 0.903
KXB54057.1
DNA polymerase III, beta subunit; KEGG: eyy:EGYY_00020 1.3e-48 hypothetical protein; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.67.
  
 
 0.898
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.872
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.862
KXB53319.1
Putative ATP-dependent DNA helicase PcrA; KEGG: eyy:EGYY_24620 1.1e-257 UvrD; superfamily I DNA helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 
 
0.801
KXB54048.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 0.796
KXB53237.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.790
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
 
 0.783
Your Current Organism:
Coriobacteriales bacterium DNF00809
NCBI taxonomy Id: 1588753
Other names: C. bacterium DNF00809
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