STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB54140.1KEGG: sez:Sez_0524 1.5e-143 nrdF; ribonucleotide-diphosphate reductase subunit beta; K00526 ribonucleoside-diphosphate reductase beta chain. (367 aa)    
Predicted Functional Partners:
KXB54142.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 0.999
nrdI
nrdI protein; Probably involved in ribonucleotide reductase function.
 
 0.998
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.821
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.814
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.781
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.768
KXB48844.1
KEGG: shi:Shel_04760 0. anaerobic ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.627
KXB48908.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: dca:Desca_0979 2.2e-76 glutamate synthase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.477
KXB54143.1
KEGG: gvg:HMPREF0421_20970 1.3e-48 pdxH; pyridoxamine 5'-phosphate oxidase K07006; Psort location: Cytoplasmic, score: 7.50.
       0.469
KXB54129.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
    
  0.451
Your Current Organism:
Coriobacteriales bacterium DNF00809
NCBI taxonomy Id: 1588753
Other names: C. bacterium DNF00809
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