STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaAReplication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (537 aa)    
Predicted Functional Partners:
KXB54057.1
DNA polymerase III, beta subunit; KEGG: eyy:EGYY_00020 1.3e-48 hypothetical protein; K02338 DNA polymerase III subunit beta; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.989
KXB54048.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.955
KXB54055.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: scl:sce0516 0.00025 two-component sensor histidine kinase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.856
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.816
KXB52654.1
Sporulation initiation inhibitor protein Soj; KEGG: ase:ACPL_8380 6.9e-66 parA; formate-tetrahydrofolate ligase K03496; Psort location: CytoplasmicMembrane, score: 8.78.
 
 
 0.793
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.718
secF
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.670
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.664
rpmH
Ribosomal protein L34; KEGG: mmn:midi_01062 8.1e-08 rpmH; 50S ribosomal protein L34P K02914; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.660
KXB48974.1
KEGG: eyy:EGYY_25950 0. RecJ; single-stranded DNA-specific exonuclease; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 9.89.
  
  
 0.629
Your Current Organism:
Coriobacteriales bacterium DNF00809
NCBI taxonomy Id: 1588753
Other names: C. bacterium DNF00809
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