STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. (329 aa)    
Predicted Functional Partners:
KXB53190.1
Oxidoreductase NAD-binding domain protein; KEGG: ols:Olsu_0990 2.5e-38 dihydroorotate oxidase B, electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.97.
 0.999
pyrC
Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.994
KXB48908.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: dca:Desca_0979 2.2e-76 glutamate synthase; Psort location: Cytoplasmic, score: 9.97.
 
 0.988
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.986
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 0.977
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.976
pheT
phenylalanine--tRNA ligase, beta subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.957
pyrB
KEGG: ele:Elen_1674 2.0e-132 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.951
pyrR
Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.926
KXB48217.1
KEGG: ccu:Ccur_09770 0. pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
    
 0.834
Your Current Organism:
Coriobacteriales bacterium DNF00809
NCBI taxonomy Id: 1588753
Other names: C. bacterium DNF00809
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