STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB48154.1Protein FolC; KEGG: eyy:EGYY_25960 1.4e-97 hypothetical protein; K11754 dihydrofolate synthase / folylpolyglutamate synthase. (518 aa)    
Predicted Functional Partners:
KXB48068.1
KEGG: cyb:CYB_2922 1.1e-58 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 7.50.
 
 0.999
KXB48153.1
Hypothetical protein.
       0.773
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.715
folE
GTP cyclohydrolase I; KEGG: ccu:Ccur_11630 7.0e-73 GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.710
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.657
fhs
KEGG: ccu:Ccur_02250 5.1e-196 Formate-tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.655
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
       0.605
KXB48155.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.582
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.541
KXB51578.1
Oxidoreductase.
     
 0.531
Your Current Organism:
Coriobacteriales bacterium DNF00809
NCBI taxonomy Id: 1588753
Other names: C. bacterium DNF00809
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