| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB93593.1 | KXB93595.1 | HMPREF3191_00382 | HMPREF3191_00384 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | 0.840 |
| KXB93593.1 | KXB93596.1 | HMPREF3191_00382 | HMPREF3191_00385 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.933 |
| KXB93593.1 | KXB93600.1 | HMPREF3191_00382 | HMPREF3191_00389 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | KEGG: med:MELS_0085 2.9e-106 arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.806 |
| KXB93593.1 | KXB93601.1 | HMPREF3191_00382 | HMPREF3191_00390 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | Putative 3-deoxy-manno-octulosonate-8-phosphatase; KEGG: str:Sterm_0149 6.7e-36 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270; Psort location: Cytoplasmic, score: 7.50. | 0.758 |
| KXB93593.1 | KXB93602.1 | HMPREF3191_00382 | HMPREF3191_00391 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | KEGG: vpr:Vpar_0546 6.2e-65 lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase. | 0.808 |
| KXB93593.1 | kdsA | HMPREF3191_00382 | HMPREF3191_00388 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | 3-deoxy-8-phosphooctulonate synthase; KEGG: vpr:Vpar_0543 3.6e-101 2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. | 0.839 |
| KXB93593.1 | kdsB | HMPREF3191_00382 | HMPREF3191_00387 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.847 |
| KXB93593.1 | lpxB | HMPREF3191_00382 | HMPREF3191_00383 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.942 |
| KXB93593.1 | lpxK | HMPREF3191_00382 | HMPREF3191_00386 | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.941 |
| KXB93595.1 | KXB93593.1 | HMPREF3191_00384 | HMPREF3191_00382 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.840 |
| KXB93595.1 | KXB93596.1 | HMPREF3191_00384 | HMPREF3191_00385 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.812 |
| KXB93595.1 | KXB93600.1 | HMPREF3191_00384 | HMPREF3191_00389 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: med:MELS_0085 2.9e-106 arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.796 |
| KXB93595.1 | KXB93601.1 | HMPREF3191_00384 | HMPREF3191_00390 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | Putative 3-deoxy-manno-octulosonate-8-phosphatase; KEGG: str:Sterm_0149 6.7e-36 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270; Psort location: Cytoplasmic, score: 7.50. | 0.786 |
| KXB93595.1 | KXB93602.1 | HMPREF3191_00384 | HMPREF3191_00391 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: vpr:Vpar_0546 6.2e-65 lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase. | 0.745 |
| KXB93595.1 | kdsA | HMPREF3191_00384 | HMPREF3191_00388 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | 3-deoxy-8-phosphooctulonate synthase; KEGG: vpr:Vpar_0543 3.6e-101 2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family. | 0.811 |
| KXB93595.1 | kdsB | HMPREF3191_00384 | HMPREF3191_00387 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.811 |
| KXB93595.1 | lpxB | HMPREF3191_00384 | HMPREF3191_00383 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.836 |
| KXB93595.1 | lpxK | HMPREF3191_00384 | HMPREF3191_00386 | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.855 |
| KXB93596.1 | KXB93593.1 | HMPREF3191_00385 | HMPREF3191_00382 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Hypothetical protein; KEGG: hmc:HYPMC_2860 2.9e-19 lipid-A-disaccharide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.933 |
| KXB93596.1 | KXB93595.1 | HMPREF3191_00385 | HMPREF3191_00384 | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KEGG: med:MELS_0090 8.3e-189 lipid A export permease/ATP-binding protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00. | 0.812 |