close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB88544.1Site-specific recombinase, phage integrase family; KEGG: apb:SAR116_1837 0.00017 phage integrase K03733; Belongs to the 'phage' integrase family. (327 aa)    
Predicted Functional Partners:
KXB89545.1
KEGG: clj:CLJU_c09340 0. pyruvate:ferredoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50.
    
 0.737
KXB93843.1
Hypothetical protein.
 
    0.657
KXB91197.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 8.16.
  
     0.636
KXB93604.1
OstA-like protein.
  
     0.615
KXB89113.1
Hypothetical protein; KEGG: bme:BMEI1894 2.1e-05 gramicidin S biosynthesis grsT protein K09800.
  
     0.591
KXB89109.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
  
     0.573
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.550
KXB94025.1
Hypothetical protein.
  
     0.536
KXB93603.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.534
KXB93821.1
comF family protein; KEGG: chu:CHU_3495 4.9e-17 purF; amidophosphoribosyltransferase K00764; Psort location: CytoplasmicMembrane, score: 8.16.
   
    0.527
Your Current Organism:
Veillonellaceae bacterium DNF00626
NCBI taxonomy Id: 1588754
Other names: V. bacterium DNF00626
Server load: medium (44%) [HD]