node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDU31212.1 | SDU41304.1 | SAMN04488548_134466 | SAMN04488548_1341005 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | 0.998 |
SDU31212.1 | SDU54755.1 | SAMN04488548_134466 | SAMN04488548_1342038 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase. | 0.948 |
SDU31212.1 | SDU55139.1 | SAMN04488548_134466 | SAMN04488548_1342073 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ABC-type metal ion transport system, substrate-binding protein/surface antigen. | 0.412 |
SDU31212.1 | metK | SAMN04488548_134466 | SAMN04488548_134561 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.982 |
SDU31212.1 | metN | SAMN04488548_134466 | SAMN04488548_1342071 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ABC-type methionine transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.877 |
SDU35476.1 | metN | SAMN04488548_134684 | SAMN04488548_1342071 | Iron (metal) dependent repressor, DtxR family. | ABC-type methionine transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.804 |
SDU36902.1 | metN | SAMN04488548_134754 | SAMN04488548_1342071 | Iron (metal) dependent repressor, DtxR family. | ABC-type methionine transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.810 |
SDU41304.1 | SDU31212.1 | SAMN04488548_1341005 | SAMN04488548_134466 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.998 |
SDU41304.1 | SDU54755.1 | SAMN04488548_1341005 | SAMN04488548_1342038 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine beta-synthase. | 0.820 |
SDU41304.1 | SDU55128.1 | SAMN04488548_1341005 | SAMN04488548_1342072 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | ABC-type methionine transport system, permease component. | 0.511 |
SDU41304.1 | SDU55139.1 | SAMN04488548_1341005 | SAMN04488548_1342073 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | ABC-type metal ion transport system, substrate-binding protein/surface antigen. | 0.500 |
SDU41304.1 | metK | SAMN04488548_1341005 | SAMN04488548_134561 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.901 |
SDU41304.1 | metN | SAMN04488548_1341005 | SAMN04488548_1342071 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | ABC-type methionine transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.827 |
SDU54755.1 | SDU31212.1 | SAMN04488548_1342038 | SAMN04488548_134466 | Cystathionine beta-synthase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
SDU54755.1 | SDU41304.1 | SAMN04488548_1342038 | SAMN04488548_1341005 | Cystathionine beta-synthase. | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | 0.820 |
SDU54755.1 | metK | SAMN04488548_1342038 | SAMN04488548_134561 | Cystathionine beta-synthase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.533 |
SDU54755.1 | metN | SAMN04488548_1342038 | SAMN04488548_1342071 | Cystathionine beta-synthase. | ABC-type methionine transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.768 |
SDU55104.1 | SDU55128.1 | SAMN04488548_1342070 | SAMN04488548_1342072 | FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. | ABC-type methionine transport system, permease component. | 0.816 |
SDU55104.1 | SDU55139.1 | SAMN04488548_1342070 | SAMN04488548_1342073 | FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. | ABC-type metal ion transport system, substrate-binding protein/surface antigen. | 0.812 |
SDU55104.1 | SDU55149.1 | SAMN04488548_1342070 | SAMN04488548_1342074 | FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. | Uncharacterized membrane protein. | 0.674 |