STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykUnannotated protein; Belongs to the pyruvate kinase family. (586 aa)    
Predicted Functional Partners:
eno
Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.999
pfkA
Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
 0.996
pgi
Unannotated protein; Belongs to the GPI family.
  
 
 0.995
gap
Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.986
fba
Unannotated protein.
  
 0.978
BB562_12715
Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.978
ldh
Unannotated protein; Catalyzes the conversion of lactate to pyruvate.
  
 0.974
rplB
Unannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.974
rplE
Unannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
 
 0.972
rplX
Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
   0.972
Your Current Organism:
Lactobacillus pentosus
NCBI taxonomy Id: 1589
Other names: ATCC 8041, CCUG 33455, CIP 103156, DSM 20314, L. pentosus, LMG 10755, LMG:10755, NCAIM B.01727, NCCB 32014, NCDO 363, NCIMB 8026, NRRL B-227, NRRL B-473
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.