| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Daro_1432 | Daro_3207 | Daro_1432 | Daro_3207 | Conserved hypothetical protein. | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.436 |
| Daro_1856 | Daro_3207 | Daro_1856 | Daro_3207 | Conserved hypothetical protein. | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.436 |
| Daro_3207 | Daro_1432 | Daro_3207 | Daro_1432 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Conserved hypothetical protein. | 0.436 |
| Daro_3207 | Daro_1856 | Daro_3207 | Daro_1856 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Conserved hypothetical protein. | 0.436 |
| Daro_3207 | Daro_3209 | Daro_3207 | Daro_3209 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Biopolymer transport protein ExbD/TolR. | 0.817 |
| Daro_3207 | Daro_3210 | Daro_3207 | Daro_3210 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | MotA/TolQ/ExbB proton channel. | 0.808 |
| Daro_3207 | adk | Daro_3207 | Daro_3205 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.684 |
| Daro_3207 | hppA | Daro_3207 | Daro_3203 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Inorganic H+ pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.531 |
| Daro_3207 | kdsB | Daro_3207 | Daro_3206 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.879 |
| Daro_3207 | lpxK | Daro_3207 | Daro_3208 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.850 |
| Daro_3207 | pfp | Daro_3207 | Daro_3204 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.605 |
| Daro_3207 | xseA | Daro_3207 | Daro_3211 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.513 |
| Daro_3209 | Daro_3207 | Daro_3209 | Daro_3207 | Biopolymer transport protein ExbD/TolR. | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.817 |
| Daro_3209 | Daro_3210 | Daro_3209 | Daro_3210 | Biopolymer transport protein ExbD/TolR. | MotA/TolQ/ExbB proton channel. | 0.990 |
| Daro_3209 | adk | Daro_3209 | Daro_3205 | Biopolymer transport protein ExbD/TolR. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.663 |
| Daro_3209 | hppA | Daro_3209 | Daro_3203 | Biopolymer transport protein ExbD/TolR. | Inorganic H+ pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.533 |
| Daro_3209 | kdsB | Daro_3209 | Daro_3206 | Biopolymer transport protein ExbD/TolR. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.841 |
| Daro_3209 | lpxK | Daro_3209 | Daro_3208 | Biopolymer transport protein ExbD/TolR. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.844 |
| Daro_3209 | pfp | Daro_3209 | Daro_3204 | Biopolymer transport protein ExbD/TolR. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.593 |
| Daro_3209 | xseA | Daro_3209 | Daro_3211 | Biopolymer transport protein ExbD/TolR. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.513 |