| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Daro_2832 | Daro_3207 | Daro_2832 | Daro_3207 | ComEC/Rec2-related protein:DNA internalization-related competence protein ComEC/Rec2. | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.406 |
| Daro_2832 | Daro_3212 | Daro_2832 | Daro_3212 | ComEC/Rec2-related protein:DNA internalization-related competence protein ComEC/Rec2. | Manganese and iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.418 |
| Daro_3207 | Daro_2832 | Daro_3207 | Daro_2832 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | ComEC/Rec2-related protein:DNA internalization-related competence protein ComEC/Rec2. | 0.406 |
| Daro_3207 | Daro_3209 | Daro_3207 | Daro_3209 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Biopolymer transport protein ExbD/TolR. | 0.818 |
| Daro_3207 | Daro_3210 | Daro_3207 | Daro_3210 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | MotA/TolQ/ExbB proton channel. | 0.811 |
| Daro_3207 | Daro_3212 | Daro_3207 | Daro_3212 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Manganese and iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.408 |
| Daro_3207 | adk | Daro_3207 | Daro_3205 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.663 |
| Daro_3207 | hppA | Daro_3207 | Daro_3203 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Inorganic H+ pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.532 |
| Daro_3207 | kdsB | Daro_3207 | Daro_3206 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.878 |
| Daro_3207 | lpxK | Daro_3207 | Daro_3208 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.851 |
| Daro_3207 | pfp | Daro_3207 | Daro_3204 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.605 |
| Daro_3207 | xseA | Daro_3207 | Daro_3211 | Protein of unknown function DUF343; Belongs to the UPF0434 family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.492 |
| Daro_3209 | Daro_3207 | Daro_3209 | Daro_3207 | Biopolymer transport protein ExbD/TolR. | Protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.818 |
| Daro_3209 | Daro_3210 | Daro_3209 | Daro_3210 | Biopolymer transport protein ExbD/TolR. | MotA/TolQ/ExbB proton channel. | 0.986 |
| Daro_3209 | Daro_3212 | Daro_3209 | Daro_3212 | Biopolymer transport protein ExbD/TolR. | Manganese and iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.515 |
| Daro_3209 | adk | Daro_3209 | Daro_3205 | Biopolymer transport protein ExbD/TolR. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.660 |
| Daro_3209 | hppA | Daro_3209 | Daro_3203 | Biopolymer transport protein ExbD/TolR. | Inorganic H+ pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.514 |
| Daro_3209 | kdsB | Daro_3209 | Daro_3206 | Biopolymer transport protein ExbD/TolR. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.843 |
| Daro_3209 | lpxK | Daro_3209 | Daro_3208 | Biopolymer transport protein ExbD/TolR. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.851 |
| Daro_3209 | pfp | Daro_3209 | Daro_3204 | Biopolymer transport protein ExbD/TolR. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.603 |