STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPF_2562Fumarate hydratase. (183 aa)    
Predicted Functional Partners:
DPF_2561
Fumarate hydratase.
 
 0.999
DPF_2560
Fumarate reductase.
  
 
 0.978
DPF_2649
Malate dehydrogenase.
 
 
 0.974
DPF_2559
Fumarate reductase flavoprotein subunit.
  
 
 0.972
DPF_2558
Fumarate reductase.
  
 
 0.965
sucD
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.959
DPF_1829
NADH-ubiquinone oxidoreductase subunit 3.
   
 
 0.837
argH
Argininosuccinate lyase.
    
 0.803
DPF_0334
Pyruvate-ferredoxin oxidoreductase.
    
 0.761
DPF_0352
Isocitrate dehydrogenase.
  
  
 0.739
Your Current Organism:
Desulfoplanes formicivorans
NCBI taxonomy Id: 1592317
Other names: D. formicivorans, DSM 28890, Desulfomicrobiaceae bacterium Pf12B, Desulfoplanes formicivorans Watanabe et al. 2015, NBRC 110391, strain Pf12B
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.