STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rodARod shape determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (436 aa)    
Predicted Functional Partners:
SIP99816.1
Peptidoglycan glycosyltransferase.
 
 0.996
SIQ05871.1
Cell division protein FtsI (penicillin-binding protein 3).
 
 0.953
SIP99744.1
Rod shape-determining protein MreB.
 
 
 0.944
SIP99769.1
Rod shape-determining protein MreC.
 
  
 0.930
murG
UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.924
SIQ04748.1
Cell division protein FtsQ; Essential cell division protein.
  
 
 0.894
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.891
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.846
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
   
 
 0.826
SIP89630.1
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Belongs to the MurCDEF family.
 
  
 0.824
Your Current Organism:
Alkalispirochaeta americana
NCBI taxonomy Id: 159291
Other names: A. americana, ATCC BAA-392, Alkalispirochaeta americana (Hoover et al. 2003) Sravanthi et al. 2016, DSM 14872, Spirochaeta americana, Spirochaeta americana Hoover et al. 2003, Spirochaeta sp. ASpG1, strain ASpG1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.