STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa)    
Predicted Functional Partners:
SIP97184.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
SIP97206.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.998
SIQ21204.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.994
SIQ21250.1
2-oxoisovalerate dehydrogenase E1 component.
 
0.989
SIP97226.1
Dihydrolipoamide dehydrogenase.
 
 0.988
SIQ21224.1
Dihydrolipoamide dehydrogenase.
 
 0.952
SIP88270.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 0.920
SIQ39904.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
    
 0.834
SIP98138.1
Acetolactate synthase, large subunit.
  
 
 0.833
SIQ35886.1
Transketolase; Belongs to the transketolase family.
  
 
 0.831
Your Current Organism:
Alkalispirochaeta americana
NCBI taxonomy Id: 159291
Other names: A. americana, ATCC BAA-392, Alkalispirochaeta americana (Hoover et al. 2003) Sravanthi et al. 2016, DSM 14872, Spirochaeta americana, Spirochaeta americana Hoover et al. 2003, Spirochaeta sp. ASpG1, strain ASpG1
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