node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIQ05008.1 | SIQ54965.1 | SAMN05920897_10327 | SAMN05920897_110125 | Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.656 |
SIQ05008.1 | hisH | SAMN05920897_10327 | SAMN05920897_11515 | Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.662 |
SIQ18838.1 | SIQ54965.1 | SAMN05920897_10512 | SAMN05920897_110125 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.854 |
SIQ18838.1 | hisA | SAMN05920897_10512 | SAMN05920897_107124 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.409 |
SIQ54965.1 | SIQ05008.1 | SAMN05920897_110125 | SAMN05920897_10327 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. | 0.656 |
SIQ54965.1 | SIQ18838.1 | SAMN05920897_110125 | SAMN05920897_10512 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.854 |
SIQ54965.1 | SIQ89729.1 | SAMN05920897_110125 | SAMN05920897_11777 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | ATP phosphoribosyltransferase regulatory subunit. | 0.628 |
SIQ54965.1 | aroA | SAMN05920897_110125 | SAMN05920897_110124 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.802 |
SIQ54965.1 | hisA | SAMN05920897_110125 | SAMN05920897_107124 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.716 |
SIQ54965.1 | hisB | SAMN05920897_110125 | SAMN05920897_1058 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Imidazoleglycerol-phosphate dehydratase. | 0.710 |
SIQ54965.1 | hisF | SAMN05920897_110125 | SAMN05920897_11514 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.797 |
SIQ54965.1 | hisH | SAMN05920897_110125 | SAMN05920897_11515 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.753 |
SIQ54965.1 | serC | SAMN05920897_110125 | SAMN05920897_106110 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.695 |
SIQ54965.1 | trpF | SAMN05920897_110125 | SAMN05920897_1089 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Indole-3-glycerol phosphate synthase; Belongs to the TrpF family. | 0.835 |
SIQ89729.1 | SIQ54965.1 | SAMN05920897_11777 | SAMN05920897_110125 | ATP phosphoribosyltransferase regulatory subunit. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.628 |
SIQ89729.1 | hisA | SAMN05920897_11777 | SAMN05920897_107124 | ATP phosphoribosyltransferase regulatory subunit. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.915 |
SIQ89729.1 | hisB | SAMN05920897_11777 | SAMN05920897_1058 | ATP phosphoribosyltransferase regulatory subunit. | Imidazoleglycerol-phosphate dehydratase. | 0.934 |
SIQ89729.1 | hisF | SAMN05920897_11777 | SAMN05920897_11514 | ATP phosphoribosyltransferase regulatory subunit. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.951 |
SIQ89729.1 | hisH | SAMN05920897_11777 | SAMN05920897_11515 | ATP phosphoribosyltransferase regulatory subunit. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.912 |
aroA | SIQ54965.1 | SAMN05920897_110124 | SAMN05920897_110125 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.802 |