STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIQ89703.116S rRNA (guanine(966)-N(2))-methyltransferase RsmD. (183 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.871
SIQ89649.1
YggT family protein.
 
     0.832
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
       0.813
SIQ89577.1
DNA polymerase III, alpha subunit.
       0.812
SIQ89457.1
dTDP-4-amino-4,6-dideoxygalactose transaminase; Belongs to the DegT/DnrJ/EryC1 family.
       0.796
SIQ89484.1
CO or xanthine dehydrogenase, Mo-binding subunit.
       0.795
SIQ89546.1
CO or xanthine dehydrogenase, FAD-binding subunit.
       0.792
SIQ89511.1
Carbon-monoxide dehydrogenase small subunit.
       0.784
SIQ89729.1
ATP phosphoribosyltransferase regulatory subunit.
       0.721
SIQ89765.1
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.721
Your Current Organism:
Alkalispirochaeta americana
NCBI taxonomy Id: 159291
Other names: A. americana, ATCC BAA-392, Alkalispirochaeta americana (Hoover et al. 2003) Sravanthi et al. 2016, DSM 14872, Spirochaeta americana, Spirochaeta americana Hoover et al. 2003, Spirochaeta sp. ASpG1, strain ASpG1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.