STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (395 aa)    
Predicted Functional Partners:
fcl
GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.999
SIQ32659.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.963
SIR02531.1
Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.933
SIQ04375.1
dTDP-4-amino-4,6-dideoxygalactose transaminase; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.835
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
   0.773
SIQ06264.1
UDP-glucuronate decarboxylase.
  
0.719
SIQ32330.1
UDP-glucuronate 4-epimerase.
  
0.719
SIQ95227.1
L-threonine 3-dehydrogenase.
  
 0.719
SIQ89434.1
NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC.
  
  
 0.707
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
 
      0.697
Your Current Organism:
Alkalispirochaeta americana
NCBI taxonomy Id: 159291
Other names: A. americana, ATCC BAA-392, Alkalispirochaeta americana (Hoover et al. 2003) Sravanthi et al. 2016, DSM 14872, Spirochaeta americana, Spirochaeta americana Hoover et al. 2003, Spirochaeta sp. ASpG1, strain ASpG1
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