STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDY49532.18-oxo-dGTP diphosphatase. (128 aa)    
Predicted Functional Partners:
nnrE
NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...]
  
 0.977
SDY65903.1
Two-component system, NarL family, sensor histidine kinase EvgS.
  
 
 0.872
SDY64088.1
ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family.
  
 0.871
SDZ09511.1
ATP-dependent RNA helicase DeaD.
  
 0.871
SDY26965.1
Hypothetical protein.
  
 
 0.870
SDZ04820.1
PAS domain S-box-containing protein.
  
 
 0.868
SDY32923.1
Hypothetical protein.
  
 
 0.865
ribBA
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 0.851
SDY49565.1
Superfamily II DNA or RNA helicase.
 
    0.843
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.837
Your Current Organism:
Tindallia californiensis
NCBI taxonomy Id: 159292
Other names: ATCC BAA-393, CIP 107910, DSM 14871, T. californiensis, Tindallia californiensis Pikuta et al. 2003, Tindallia sp. APO, strain APO
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