STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDZ12830.12-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (162 aa)    
Predicted Functional Partners:
SDZ12847.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
SDZ12857.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase I.
  
 0.999
ribBA
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.967
SDY43487.1
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.947
SDY42531.1
Dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
  0.909
SDY45588.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.874
pheA
Prephenate dehydratase/chorismate mutase / prephenate dehydratase.
      0.770
SDZ12924.1
Aminodeoxychorismate synthase, subunit I.
 
 
 0.765
SDZ12907.1
4-amino-4-deoxychorismate lyase.
  
 
 0.757
Your Current Organism:
Tindallia californiensis
NCBI taxonomy Id: 159292
Other names: ATCC BAA-393, CIP 107910, DSM 14871, T. californiensis, Tindallia californiensis Pikuta et al. 2003, Tindallia sp. APO, strain APO
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