STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KHD22573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)    
Predicted Functional Partners:
KHD22574.1
UMUC domain-containing protein DNA-repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.998
dnaE2
DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.962
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.903
lexA
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.618
dnaE
DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.606
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.599
KHD20914.1
DNA repair protein; May be involved in recombinational repair of damaged DNA.
   
  
 0.552
KHD21955.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.472
KHD20745.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.419
KHD22446.1
Sugar dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.416
Your Current Organism:
Paraburkholderia sacchari
NCBI taxonomy Id: 159450
Other names: Burkholderia sacchari, Burkholderia sacchari Bramer et al. 2001, CCT 6771, CCUG 46043, CIP 107211, DSM 17165, IPT 101, LMG 19450, LMG:19450, P. sacchari, Paraburkholderia sacchari (Braner et al. 2001) Sawana et al. 2015
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