Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LBAT_0400Malate dehydrogenase. (540 aa)    
Predicted Functional Partners:
LBAT_0399
Malate transport protein.
 
  
 0.960
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.957
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.943
LBAT_0566
L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.943
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.943
LBAT_0944
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.819
tal
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 
 0.694
alaS
alanyl-tRNA synthase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.575
citD
Citrate lyase gamma subunit; Covalent carrier of the coenzyme of citrate lyase.
  
  
 0.571
LBAT_0824
Citrate lyase alpha subunit.
  
  
 0.558
Your Current Organism:
Lactobacillus acetotolerans
NCBI taxonomy Id: 1600
Other names: ATCC 43578, CCUG 32229, CIP 103180, DSM 20749, JCM 3825, L. acetotolerans, LMG 10751, LMG:10751, Lactobacillus acetitolerans, NBI 3014
Server load: low (28%) [HD]