mprF protein (Lactobacillus acetotolerans) - STRING interaction network

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mprF

Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (341 aa)

Predicted Functional Partners:

LBAT_0491

0.911

LBAT_0490

0.893

LBAT_0493

0.694

LBAT_0483

0.681

LBAT_1185

0.644

LBAT_0569

0.624

rpoB

0.619

LBAT_1073

0.583

LBAT_0877

0.531

LBAT_0016

0.486

Your Current Organism:

Lactobacillus acetotolerans

NCBI taxonomy Id: 1600
Other names: ATCC 43578, CCUG 32229, CIP 103180, DSM 20749, JCM 3825, L. acetotolerans, LMG 10751, LMG:10751, Lactobacillus acetitolerans, NBI 3014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LBAT_0016	mprF	LBAT_0016	LBAT_0492	Conserved hypothetical protein.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.486
LBAT_0483	mprF	LBAT_0483	LBAT_0492	Conserved hypothetical protein.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.681
LBAT_0490	LBAT_0491	LBAT_0490	LBAT_0491	Glycosyltransferase.	Glycosyltransferase.	0.996
LBAT_0490	LBAT_0493	LBAT_0490	LBAT_0493	Glycosyltransferase.	Phosphoglycerol transferase.	0.704
LBAT_0490	mprF	LBAT_0490	LBAT_0492	Glycosyltransferase.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.893
LBAT_0491	LBAT_0490	LBAT_0491	LBAT_0490	Glycosyltransferase.	Glycosyltransferase.	0.996
LBAT_0491	LBAT_0493	LBAT_0491	LBAT_0493	Glycosyltransferase.	Phosphoglycerol transferase.	0.716
LBAT_0491	mprF	LBAT_0491	LBAT_0492	Glycosyltransferase.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.911
LBAT_0493	LBAT_0490	LBAT_0493	LBAT_0490	Phosphoglycerol transferase.	Glycosyltransferase.	0.704
LBAT_0493	LBAT_0491	LBAT_0493	LBAT_0491	Phosphoglycerol transferase.	Glycosyltransferase.	0.716
LBAT_0493	mprF	LBAT_0493	LBAT_0492	Phosphoglycerol transferase.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.694
LBAT_0569	LBAT_0877	LBAT_0569	LBAT_0877	Penicillin-binding protein.	Conserved hypothetical protein.	0.633
LBAT_0569	LBAT_1185	LBAT_0569	LBAT_1185	Penicillin-binding protein.	CDP-diacylglycerol- phosphatephosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.557
LBAT_0569	mprF	LBAT_0569	LBAT_0492	Penicillin-binding protein.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.624
LBAT_0877	LBAT_0569	LBAT_0877	LBAT_0569	Conserved hypothetical protein.	Penicillin-binding protein.	0.633
LBAT_0877	mprF	LBAT_0877	LBAT_0492	Conserved hypothetical protein.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.531
LBAT_1073	mprF	LBAT_1073	LBAT_0492	Conserved hypothetical protein.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.583
LBAT_1185	LBAT_0569	LBAT_1185	LBAT_0569	CDP-diacylglycerol- phosphatephosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Penicillin-binding protein.	0.557
LBAT_1185	mprF	LBAT_1185	LBAT_0492	CDP-diacylglycerol- phosphatephosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.644
mprF	LBAT_0016	LBAT_0492	LBAT_0016	Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Conserved hypothetical protein.	0.486

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