STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)    
Predicted Functional Partners:
LBAT_0816
Fumarate reductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.998
LBAT_0400
Malate dehydrogenase.
  
 
 0.955
LBAT_1363
NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.852
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
    
 0.775
LBAT_0078
Fumarate reductase flavoprotein subunit.
  
 
 0.737
LBAT_0080
Fumarate reductase flavoprotein subunit.
  
 
 0.737
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.693
LBAT_0784
Fumarate reductase.
  
 
 0.612
metG
methionyl-tRNA synthase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
     
 0.600
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 
 0.588
Your Current Organism:
Lactobacillus acetotolerans
NCBI taxonomy Id: 1600
Other names: ATCC 43578, CCUG 32229, CIP 103180, DSM 20749, JCM 3825, L. acetotolerans, LMG 10751, LMG:10751, Lactobacillus acetitolerans, NBI 3014
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.