Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LBAT_1227hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (403 aa)    
Predicted Functional Partners:
LBAT_0873
Mevalonate kinase.
 0.999
LBAT_1226
hydroxymethylglutaryl-CoA synthase.
 
 0.999
LBAT_1229
Truncated acetyl-CoA acetyltransferase.
 
  
 0.981
LBAT_1228
Truncated acetyl-CoA acetyltransferase.
 
  
 0.969
LBAT_0872
Diphosphomevalonate decarboxylase.
 
  
 0.920
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.786
LBAT_0871
Phosphomevalonate kinase.
 
 
 0.701
LBAT_1542
Prenyltransferase, ubia family.
    
 
 0.639
LBAT_0638
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.549
LBAT_1323
Conserved hypothetical protein.
   
 
 0.478
Your Current Organism:
Lactobacillus acetotolerans
NCBI taxonomy Id: 1600
Other names: ATCC 43578, CCUG 32229, CIP 103180, DSM 20749, JCM 3825, L. acetotolerans, LMG 10751, LMG:10751, Lactobacillus acetitolerans, NBI 3014
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