A0A0S6XGV5 protein (fungal sp. No11243) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

A0A0S6XGV5

NMO domain-containing protein. (355 aa)

Predicted Functional Partners:

RPS0

0.588

A0A0S6X8L6

0.583

A0A0C9LY72

0.582

A0A0S6XRI6

0.582

A0A0S6XT84

0.582

A0A0S6XUM4

0.582

A0A0C9M294

0.581

A0A0S6X6K8

0.581

A0A0S6XDN6

0.581

A0A0S6XM76

0.581

Your Current Organism:

fungal sp. No11243

NCBI taxonomy Id: 1603295
Other names: f. sp. No.11243, fungal sp. No.11243

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0C9LY72	A0A0C9M294	A0A0C9LY72	A0A0C9M294	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	MRP-S28 domain-containing protein.	0.999
A0A0C9LY72	A0A0S6X6K8	A0A0C9LY72	A0A0S6X6K8	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Ribosomal_S10 domain-containing protein.	0.999
A0A0C9LY72	A0A0S6X8L6	A0A0C9LY72	A0A0S6X8L6	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
A0A0C9LY72	A0A0S6XDN6	A0A0C9LY72	A0A0S6XDN6	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	L51_S25_CI-B8 domain-containing protein.	0.998
A0A0C9LY72	A0A0S6XGV5	A0A0C9LY72	A0A0S6XGV5	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	NMO domain-containing protein.	0.582
A0A0C9LY72	A0A0S6XM76	A0A0C9LY72	A0A0S6XM76	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
A0A0C9LY72	A0A0S6XRI6	A0A0C9LY72	A0A0S6XRI6	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
A0A0C9LY72	A0A0S6XT84	A0A0C9LY72	A0A0S6XT84	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
A0A0C9LY72	A0A0S6XUM4	A0A0C9LY72	A0A0S6XUM4	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
A0A0C9LY72	RPS0	A0A0C9LY72	A0A0S6XTN0	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.999
A0A0C9M294	A0A0C9LY72	A0A0C9M294	A0A0C9LY72	MRP-S28 domain-containing protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
A0A0C9M294	A0A0S6X6K8	A0A0C9M294	A0A0S6X6K8	MRP-S28 domain-containing protein.	Ribosomal_S10 domain-containing protein.	0.999
A0A0C9M294	A0A0S6X8L6	A0A0C9M294	A0A0S6X8L6	MRP-S28 domain-containing protein.	Uncharacterized protein.	0.999
A0A0C9M294	A0A0S6XDN6	A0A0C9M294	A0A0S6XDN6	MRP-S28 domain-containing protein.	L51_S25_CI-B8 domain-containing protein.	0.999
A0A0C9M294	A0A0S6XGV5	A0A0C9M294	A0A0S6XGV5	MRP-S28 domain-containing protein.	NMO domain-containing protein.	0.581
A0A0C9M294	A0A0S6XM76	A0A0C9M294	A0A0S6XM76	MRP-S28 domain-containing protein.	Uncharacterized protein.	0.999
A0A0C9M294	A0A0S6XRI6	A0A0C9M294	A0A0S6XRI6	MRP-S28 domain-containing protein.	Uncharacterized protein.	0.999
A0A0C9M294	A0A0S6XT84	A0A0C9M294	A0A0S6XT84	MRP-S28 domain-containing protein.	Uncharacterized protein.	0.999
A0A0C9M294	A0A0S6XUM4	A0A0C9M294	A0A0S6XUM4	MRP-S28 domain-containing protein.	Uncharacterized protein.	0.999
A0A0C9M294	RPS0	A0A0C9M294	A0A0S6XTN0	MRP-S28 domain-containing protein.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.999

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Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.924

expected number of edges:

14

PPI enrichment p-value:

4.8e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 188

1.3

2.17

1.56e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 85

1.65

3.94

1.42e-15

GO:0019843

rRNA binding

3 of 28

1.56

0.8

0.0228

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 96

1.59

3.65

3.29e-15

GO:0044391

Ribosomal subunit

6 of 71

1.46

1.88

3.62e-06

GO:0015934

Large ribosomal subunit

4 of 40

1.53

1.38

0.00057

GO:0005761

Mitochondrial ribosome

3 of 26

1.6

1.07

0.0053

GO:0005762

Mitochondrial large ribosomal subunit

2 of 13

1.72

0.71

0.0410

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2525

Structural constituent of ribosome

10 of 16

2.33

8.2

1.05e-19

CL:2522

Organellar ribosome, and SRP-dependent cotranslational protein targeting to membrane

11 of 34

2.04

6.77

1.05e-19

CL:2527

Mixed, incl. L28p-like, and Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like

5 of 5

2.53

4.62

1.01e-09

CL:2541

SRP-dependent cotranslational protein targeting to membrane

4 of 8

2.23

3.01

9.67e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 93

1.61

3.81

5.20e-16

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

10 of 157

1.34

2.2

1.75e-10

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

6 of 62

1.52

1.95

4.37e-06

MAP-72689

Formation of a pool of free 40S subunits

6 of 65

1.5

1.92

4.37e-06

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

6 of 67

1.49

1.9

4.37e-06

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

6 of 67

1.49

1.9

4.37e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

7 of 74

1.51

2.19

3.06e-07

GOCC:0022626

Cytosolic ribosome

5 of 54

1.5

1.68

4.13e-05

GOCC:0015934

Large ribosomal subunit

4 of 43

1.5

1.37

0.00050

GOCC:0015935

Small ribosomal subunit

3 of 30

1.53

1.03

0.0058

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 31

1.52

1.02

0.0058

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 63

1.43

1.48

0.00012

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