STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0S6XIU8AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (750 aa)    
Predicted Functional Partners:
A0A0S6X8X6
AP-1 complex subunit gamma.
   
0.935
A0A0C9M250
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.932
A0A0S6X9M1
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.929
A0A0S6XLT5
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.925
A0A0S6XDK4
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.922
A0A0S6XJI0
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.921
A0A0S6XU96
AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.
   
 0.907
A0A0S6XAC3
Uncharacterized protein.
    
 0.892
A0A0C9LMK2
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.891
A0A0S6XA62
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.839
Your Current Organism:
fungal sp. No11243
NCBI taxonomy Id: 1603295
Other names: f. sp. No.11243, fungal sp. No.11243
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.