STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ06511.1Hypothetical protein; COG0582 Integrase; Belongs to the 'phage' integrase family. (350 aa)    
Predicted Functional Partners:
ADZ06515.1
Hypothetical protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.
 
   
 0.790
ADZ07539.1
Hypothetical protein.
 
     0.716
ADZ06513.1
Putative replication initiator protein; COG2255 Holliday junction resolvasome, helicase subunit.
       0.576
ADZ06512.1
Hypothetical protein; COG2202 FOG: PAS/PAC domain.
       0.567
ADZ07982.1
Hypothetical protein; COG1357 Uncharacterized low-complexity proteins.
 
    0.499
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.474
ADZ06843.1
Competence protein; COG1040 Predicted amidophosphoribosyltransferases.
  
    0.446
ADZ06393.1
Hypothetical protein; Belongs to the SOS response-associated peptidase family.
  
  
 0.432
ADZ07344.1
Macrolide efflux protein; COG0477 Permeases of the major facilitator superfamily.
 
   
 0.431
ADZ07423.1
COG5283 Phage-related tail protein.
  
   
 0.431
Your Current Organism:
Lactobacillus amylovorus
NCBI taxonomy Id: 1604
Other names: ATCC 33620, CCUG 27201, CIP 102989, DSM 16698 [[Lactobacillus sobrius]], DSM 20531, L. amylovorus, LMG 9496, LMG:9496, Lactobacillus acidophilus group A3, Lactobacillus sobrius, Lactobacillus sobrius Konstantinov et al. 2006, NCAIM B.01458, NCCB 100067 [[Lactobacillus sobrius]], NRRL B-4540, strain OTU171-001 [[Lactobacillus sobrius]]
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