| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ06628.1 | ADZ06629.1 | LAC30SC_02225 | LAC30SC_02230 | X-Pro dipeptidase; COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. | Catabolite control protein A; COG1609 Transcriptional regulators. | 0.869 |
| ADZ06629.1 | ADZ06628.1 | LAC30SC_02230 | LAC30SC_02225 | Catabolite control protein A; COG1609 Transcriptional regulators. | X-Pro dipeptidase; COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. | 0.869 |
| ADZ06629.1 | ADZ06814.1 | LAC30SC_02230 | LAC30SC_03210 | Catabolite control protein A; COG1609 Transcriptional regulators. | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | 0.835 |
| ADZ06629.1 | ADZ06897.1 | LAC30SC_02230 | LAC30SC_03625 | Catabolite control protein A; COG1609 Transcriptional regulators. | COG3711 Transcriptional antiterminator. | 0.554 |
| ADZ06629.1 | ADZ07717.1 | LAC30SC_02230 | LAC30SC_08080 | Catabolite control protein A; COG1609 Transcriptional regulators. | Transcriptional regulator, gntR family protein; COG2188 Transcriptional regulators. | 0.557 |
| ADZ06629.1 | ADZ08027.1 | LAC30SC_02230 | LAC30SC_09640 | Catabolite control protein A; COG1609 Transcriptional regulators. | PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.589 |
| ADZ06629.1 | ADZ08029.1 | LAC30SC_02230 | LAC30SC_09650 | Catabolite control protein A; COG1609 Transcriptional regulators. | Repressor of fructose operon; COG1349 Transcriptional regulators of sugar metabolism. | 0.658 |
| ADZ06629.1 | hprK | LAC30SC_02230 | LAC30SC_03380 | Catabolite control protein A; COG1609 Transcriptional regulators. | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] | 0.641 |
| ADZ06629.1 | pyk | LAC30SC_02230 | LAC30SC_04810 | Catabolite control protein A; COG1609 Transcriptional regulators. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.627 |
| ADZ06629.1 | pyrD | LAC30SC_02230 | LAC30SC_07710 | Catabolite control protein A; COG1609 Transcriptional regulators. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.556 |
| ADZ06629.1 | rbsK | LAC30SC_02230 | LAC30SC_02990 | Catabolite control protein A; COG1609 Transcriptional regulators. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.785 |
| ADZ06814.1 | ADZ06629.1 | LAC30SC_03210 | LAC30SC_02230 | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | Catabolite control protein A; COG1609 Transcriptional regulators. | 0.835 |
| ADZ06814.1 | ADZ08027.1 | LAC30SC_03210 | LAC30SC_09640 | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.997 |
| ADZ06814.1 | hprK | LAC30SC_03210 | LAC30SC_03380 | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] | 0.888 |
| ADZ06814.1 | pyk | LAC30SC_03210 | LAC30SC_04810 | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.769 |
| ADZ06897.1 | ADZ06629.1 | LAC30SC_03625 | LAC30SC_02230 | COG3711 Transcriptional antiterminator. | Catabolite control protein A; COG1609 Transcriptional regulators. | 0.554 |
| ADZ06897.1 | ADZ08027.1 | LAC30SC_03625 | LAC30SC_09640 | COG3711 Transcriptional antiterminator. | PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.741 |
| ADZ07717.1 | ADZ06629.1 | LAC30SC_08080 | LAC30SC_02230 | Transcriptional regulator, gntR family protein; COG2188 Transcriptional regulators. | Catabolite control protein A; COG1609 Transcriptional regulators. | 0.557 |
| ADZ08027.1 | ADZ06629.1 | LAC30SC_09640 | LAC30SC_02230 | PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | Catabolite control protein A; COG1609 Transcriptional regulators. | 0.589 |
| ADZ08027.1 | ADZ06814.1 | LAC30SC_09640 | LAC30SC_03210 | PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins. | 0.997 |