STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manXPTS system, mannose-specific IIAB component; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (336 aa)    
Predicted Functional Partners:
ADZ06650.1
PTS system mannose-specific transporter subunit IIC; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
 
 0.999
ADZ06651.1
PTS system, mannose-specific IID component; COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID.
 
 0.999
ADZ06814.1
Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins.
  
 0.999
ADZ06652.1
COG4687 Uncharacterized protein conserved in bacteria.
 
  
 0.985
ADZ07921.1
PTS system, IIA component; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
 
 
0.977
ADZ06916.1
COG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.965
ADZ06209.1
Fructokinase; COG1940 Transcriptional regulator/sugar kinase.
    
 0.871
ADZ08027.1
PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.864
ptsP
P-enolpyruvate-protein p-transferase PTSI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.742
hprK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
  
  
 0.731
Your Current Organism:
Lactobacillus amylovorus
NCBI taxonomy Id: 1604
Other names: ATCC 33620, CCUG 27201, CIP 102989, DSM 16698 [[Lactobacillus sobrius]], DSM 20531, L. amylovorus, LMG 9496, LMG:9496, Lactobacillus acidophilus group A3, Lactobacillus sobrius, Lactobacillus sobrius Konstantinov et al. 2006, NCAIM B.01458, NCCB 100067 [[Lactobacillus sobrius]], NRRL B-4540, strain OTU171-001 [[Lactobacillus sobrius]]
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