STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPP-enolpyruvate-protein p-transferase PTSI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)    
Predicted Functional Partners:
ADZ06814.1
Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins.
 
 0.999
ADZ06784.1
PTS enzyme II, ABC component; COG2190 Phosphotransferase system IIA components.
 
 0.989
ADZ08027.1
PTS system, fructose-specific enzyme II; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
  
 0.989
ADZ06583.1
PTS system, sucrose-specific IIABC component; COG1264 Phosphotransferase system IIB components.
 
 0.987
ADZ06661.1
PTS system, mannitol-specific IIA component; COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain.
    
 0.932
ADZ06781.1
PTS system, arbutin-like IIBC component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
 0.816
pfkB
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.803
ADZ07720.1
Lactose permease; COG2211 Na+/melibiose symporter and related transporters.
 
 
 0.790
manX
PTS system, mannose-specific IIAB component; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
  
  
 0.742
ADZ07938.1
PTS system sucrose-specific transporter subunit EIIBC; COG1264 Phosphotransferase system IIB components.
 
  
 0.720
Your Current Organism:
Lactobacillus amylovorus
NCBI taxonomy Id: 1604
Other names: ATCC 33620, CCUG 27201, CIP 102989, DSM 16698 [[Lactobacillus sobrius]], DSM 20531, L. amylovorus, LMG 9496, LMG:9496, Lactobacillus acidophilus group A3, Lactobacillus sobrius, Lactobacillus sobrius Konstantinov et al. 2006, NCAIM B.01458, NCCB 100067 [[Lactobacillus sobrius]], NRRL B-4540, strain OTU171-001 [[Lactobacillus sobrius]]
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