node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADZ06196.1 | pheT | LAC30SC_00010 | LAC30SC_08235 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.704 |
ADZ06196.1 | polA | LAC30SC_00010 | LAC30SC_08380 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
ADZ06196.1 | tsaE | LAC30SC_00010 | LAC30SC_03540 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0802 Predicted ATPase or kinase. | 0.505 |
ADZ06196.1 | ung | LAC30SC_00010 | LAC30SC_03525 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.656 |
ADZ06573.1 | ADZ06930.1 | LAC30SC_01930 | LAC30SC_03805 | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.721 |
ADZ06573.1 | pheT | LAC30SC_01930 | LAC30SC_08235 | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.623 |
ADZ06573.1 | rimI | LAC30SC_01930 | LAC30SC_01935 | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | COG0456 Acetyltransferases. | 0.973 |
ADZ06573.1 | tsaD | LAC30SC_01930 | LAC30SC_01940 | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.998 |
ADZ06573.1 | tsaE | LAC30SC_01930 | LAC30SC_03540 | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | COG0802 Predicted ATPase or kinase. | 0.951 |
ADZ06930.1 | ADZ06573.1 | LAC30SC_03805 | LAC30SC_01930 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.721 |
ADZ06930.1 | polA | LAC30SC_03805 | LAC30SC_08380 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.535 |
ADZ06930.1 | tsaD | LAC30SC_03805 | LAC30SC_01940 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.691 |
ADZ06930.1 | tsaE | LAC30SC_03805 | LAC30SC_03540 | Sua5 family translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | COG0802 Predicted ATPase or kinase. | 0.657 |
alr | polA | LAC30SC_01260 | LAC30SC_08380 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.490 |
alr | tsaE | LAC30SC_01260 | LAC30SC_03540 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | COG0802 Predicted ATPase or kinase. | 0.640 |
eutD | tsaE | LAC30SC_03535 | LAC30SC_03540 | COG0280 Phosphotransacetylase. | COG0802 Predicted ATPase or kinase. | 0.918 |
eutD | ung | LAC30SC_03535 | LAC30SC_03525 | COG0280 Phosphotransacetylase. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.736 |
pheT | ADZ06196.1 | LAC30SC_08235 | LAC30SC_00010 | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.704 |
pheT | ADZ06573.1 | LAC30SC_08235 | LAC30SC_01930 | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.623 |
pheT | polA | LAC30SC_08235 | LAC30SC_08380 | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.878 |