node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADZ06393.1 | xerS | LAC30SC_01005 | LAC30SC_06105 | Hypothetical protein; Belongs to the SOS response-associated peptidase family. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.432 |
ADZ06843.1 | xerS | LAC30SC_03355 | LAC30SC_06105 | Competence protein; COG1040 Predicted amidophosphoribosyltransferases. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.446 |
hslU | hslV | LAC30SC_04955 | LAC30SC_04950 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.999 |
hslU | topA | LAC30SC_04955 | LAC30SC_04935 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.872 |
hslU | xerS | LAC30SC_04955 | LAC30SC_06105 | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.486 |
hslV | hslU | LAC30SC_04950 | LAC30SC_04955 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.999 |
hslV | topA | LAC30SC_04950 | LAC30SC_04935 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.860 |
hslV | xerS | LAC30SC_04950 | LAC30SC_06105 | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.547 |
pgk | xerS | LAC30SC_03495 | LAC30SC_06105 | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.420 |
topA | hslU | LAC30SC_04935 | LAC30SC_04955 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.872 |
topA | hslV | LAC30SC_04935 | LAC30SC_04950 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.860 |
topA | xerS | LAC30SC_04935 | LAC30SC_06105 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.555 |
whiA | xerS | LAC30SC_03460 | LAC30SC_06105 | Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation. | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | 0.428 |
xerS | ADZ06393.1 | LAC30SC_06105 | LAC30SC_01005 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | Hypothetical protein; Belongs to the SOS response-associated peptidase family. | 0.432 |
xerS | ADZ06843.1 | LAC30SC_06105 | LAC30SC_03355 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | Competence protein; COG1040 Predicted amidophosphoribosyltransferases. | 0.446 |
xerS | hslU | LAC30SC_06105 | LAC30SC_04955 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.486 |
xerS | hslV | LAC30SC_06105 | LAC30SC_04950 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.547 |
xerS | pgk | LAC30SC_06105 | LAC30SC_03495 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.420 |
xerS | topA | LAC30SC_06105 | LAC30SC_04935 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.555 |
xerS | whiA | LAC30SC_06105 | LAC30SC_03460 | Site-specific tyrosine recombinase XerS; COG0582 Integrase; Belongs to the 'phage' integrase family. | Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation. | 0.428 |